High Shear Granulation

 PHARMX high-shear granulator

For cosmetics, pharma and biologic tablets, nutraceuticals, agriculture, and food ingredients, high-shear granulation is an effective way to turn powders into dense granules. The process can achieve uniform results relatively quickly.

In high-shear granulation, dry powders are mixed in a bowl using a rotating impeller that spins the powders into a vortex. Once the powders are blended, a liquid binder or water is added to the powder so the particles will stick together. A high-speed chopper shears the granules and removes air. This process continues until the desired granule size and density are achieved. 

Procédé à haut cisaillement

To create the granules, powders are added to the mixing bowl and the bowl is sealed. A large impeller rotates at slow speeds, spinning the powders into a vortex. After the powders are blended together, liquid is added to the product using a pump or pressurized container. A high-speed chopper tool located in the bowl shears the granules and removes air. The mixing continues until the desired granule size and density are achieved.

 

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