Mezcla y granulación eficaces
Para una mezcla homogénea y una granulación eficaz, los granuladores de alto cizallamiento PHARMX® proporcionan una mezcla totalmente personalizable y accionada por el fondo con resultados superiores que pueden aumentar el valor y el rendimiento de sus productos finales.
La serie PHARMX, equipada con un impulsor de mezcla de fondo y un picador lateral, garantiza una mezcla uniforme en una amplia gama de modelos de I+D, piloto y de producción. Además, puede trabajar con la cuba casi a plena capacidad, maximizando su inversión en equipos.
PHARMX PX1
Laboratory-scale units provide effective high-shear granulation for small batches.
PHARMX PX25–PX100
Mid-sized systems offer a wide range of options for processing larger batches intended for clinical trial or small-scale production.
PHARMX PX150–PX1250
Large-scale systems are ideal for granulating very large batches, accommodating up to 1,250 liters of material.
MIXER SPECIFICATIONS |
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PX1 | PX25 | PX50 | PX100 | PX150 | PX250 | PX400 | PX600 | PX1250 | |
Total Bowl Vol. (L) | 1, 2, 4, 6, 8, 13 | 31 | 58 | 119 | 162 | 274 | 432 | 633 | 1286 |
Charge- Max. Liters @ Light Bulk, 0.3 - 0.5 | 0.9 - 7.5 | 28 | 58 | 107 | 150 | 246 | 389 | 569 | 1157 |
Charge- Min. Liters | 0.3 - 2.5 | 8 | 15 | 30 | 42 | 69 | 109 | 159 | 324 |
Impeller Max. Speed (RPM) | 950 | 354 | 289 | 227 | 205 | 172 | 148 | 130 | 103 |
Impeller Power (HP) | 0.5 | 3 | 5 | 10 | 15 | 40 | 50 | 75 | 150 |
Chopper Speed Range (RPM) | 1500 - 9750 | 500 - 4000 | 500 - 4000 | 500 - 4000 | 500 - 4000 | 500 - 4000 | 500 - 3000 | 500 - 3000 | 500 - 3000 |
Chopper Power (HP) | 0.25 | 1 | 2 | 5 | 7.5 | 10 | 15 | 20 | 40 |
Optimize Every Batch
Uniform, Maximized Mixing
The dome-shaped lid permits product to perform a complete rollover as it moves up the side of the vessel wall. This results in efficient mixing, even when running at larger operating capacities.
Constant Tip Speed
Impeller and chopper tip speed is one of the most important factors in high-shear granulation scale-up. All PHARMX bowls are designed to maintain a constant maximum tip speed, and each tool offers infinitely adjustable speeds, to ease the shift from lab to pilot to production.
Safe Processing of Hazardous Compounds
Interchangeable bowls support the processing of potent compounds requiring total containment. Charging and discharging from the mixer bowl is completely contained, and bowls can be removed from the console and placed in a glove box or flexible containment structure without dusting.
Auto-Cleaning and Seal Purging Systems
Fluid Air systems utilize a recipe that flushes and drains the seal purge system and cleans the bowl, tools, and discharge. Combined with a liftable tool system, this greatly simplifies cleaning. What's more, The multistage seal purging system permits operating at low and high seal flows. This helps prevent dusting when loading and allows setting of the flow to match your products' characteristics.